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BIOMARKER:

MYC rearrangement + BCL6 rearrangement

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Other names: BCL6, BCL5, BCL6A, LAZ3, ZBTB27, ZNF51, B-cell CLL/lymphoma 6, MYC, bHLHe39, c-Myc, MYCC, V-myc avian myelocytomatosis viral oncogene homolog
Entrez ID:
MYC rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
lisocabtagene maraleucel
Sensitive: A2 - Guideline
MYC rearrangement + BCL6 rearrangement
NHL
ibrutinib
Sensitive: C3 – Early Trials
MYC rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
EPOCH-R
Sensitive: C3 – Early Trials
MYC rearrangement + BCL6 rearrangement
Follicular Lymphoma
EPOCH-R
Resistant: C3 – Early Trials
MYC rearrangement + BCL6 rearrangement
Diffuse Large B Cell Lymphoma
C-RICE
Sensitive: C3 – Early Trials