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BIOMARKER:
MSH6 mutation
i
Other names:
MSH6, GTBP, MutS homolog 6
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Entrez ID:
2956
Related biomarkers:
Expression
Mutation
CNA
Others
‹
MSH2 deletion + MSH6 deletion (3)
MSH6 deletion (1)
MSH2 deletion + MSH6 deletion (0)
MSH2 deletion + MSH6 deletion (3)
MSH6 deletion (1)
MSH2 deletion + MSH6 deletion (0)
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MSH6 mutation
Gastric Cancer
MSH6 mutation
Gastric Cancer
tremelimumab
Sensitive: C2 – Inclusion Criteria
tremelimumab
Sensitive
:
C2
tremelimumab
Sensitive: C2 – Inclusion Criteria
tremelimumab
Sensitive
:
C2
MSH6 mutation
Gastric Cancer
MSH6 mutation
Gastric Cancer
durvalumab
Sensitive: C2 – Inclusion Criteria
durvalumab
Sensitive
:
C2
durvalumab
Sensitive: C2 – Inclusion Criteria
durvalumab
Sensitive
:
C2
MSH6 mutation
Colorectal Cancer
MSH6 mutation
Colorectal Cancer
5-fluorouracil + oxaliplatin
Resistant: C3 – Early Trials
5-fluorouracil + oxaliplatin
Resistant
:
C3
5-fluorouracil + oxaliplatin
Resistant: C3 – Early Trials
5-fluorouracil + oxaliplatin
Resistant
:
C3
MSH6 mutation
Triple Negative Breast Cancer
MSH6 mutation
Triple Negative Breast Cancer
olaparib
Sensitive: C3 – Early Trials
olaparib
Sensitive
:
C3
olaparib
Sensitive: C3 – Early Trials
olaparib
Sensitive
:
C3
MSH6 mutation
Rectal Cancer
MSH6 mutation
Rectal Cancer
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
MSH6 mutation
Endometrial Cancer
MSH6 mutation
Endometrial Cancer
nivolumab
Sensitive: C4 – Case Studies
nivolumab
Sensitive
:
C4
nivolumab
Sensitive: C4 – Case Studies
nivolumab
Sensitive
:
C4
MSH6 mutation
Breast Cancer
MSH6 mutation
Breast Cancer
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
MSH6 mutation
Germ Cell Tumors
MSH6 mutation
Germ Cell Tumors
camrelizumab
Sensitive: C4 – Case Studies
camrelizumab
Sensitive
:
C4
camrelizumab
Sensitive: C4 – Case Studies
camrelizumab
Sensitive
:
C4
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