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BIOMARKER:

MSH2 mutation

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Other names: MSH2, MutS Homolog 2, HMSH2, MutS (E. Coli) Homolog 2, MutS Homolog 2, Nonpolyposis Type 1, DNA Mismatch Repair Protein Msh2, MutS Protein Homolog 2, HNPCC1, HNPCC, LCFS2, COCA1, FCC1
Entrez ID:
Related biomarkers:
MSH2 mutation
Gastric Cancer
CP-675206
Sensitive: C2 – Inclusion Criteria
MSH2 mutation
Gastric Cancer
durvalumab
Sensitive: C2 – Inclusion Criteria
MSH2 mutation
Pancreatic Ductal Adenocarcinoma
FOLFIRINOX
Sensitive: C3 – Early Trials
MSH2 mutation
CRC
5-fluorouracil + oxaliplatin
Resistant: C3 – Early Trials
MSH2 mutation
Adrenal Cortex Carcinoma
pembrolizumab
Sensitive: C4 – Case Studies