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BIOMARKER:

MSH2 mutation + MSH6 mutation + BRCA1 mutation

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Entrez ID:

672; 2956; 4436

Related biomarkers:

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HRD + BRCA1 mutation (7)

BRCA1 mutation + HR positive (3)

BRCA1 mutation + TMB-H (3)

BRCA1 2080delA + CCNE1 overexpression (2)

BRCA1 mutation + HER-2 negative (2)

HR negative + BRCA1 mutation (2)

HR positive + BRCA1 mutation (2)

BAP1 negative + BRCA1 mutation (1)

BRCA1 hypermethylation (1)

BRCA1 mutation + AKR1C3 overexpression (1)

BRCA1 mutation + BRCA2 mutation + TMB-H (1)

BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)

BRCA1 mutation + PD-L1 expression (1)

BRCA1 mutation + RAD51B deletion (1)

BRCA1 mutation + RB1 deletion (1)

BRCA1 promoter methylation (1)

EGFR mutation + BRCA1 overexpression (1)

EGFR mutation + BRCA1 underexpression (1)

HR positive + BRCA1 mutation + PALB2 mutation (1)

PTEN deletion + BRCA1 mutation (1)

MSH6 mutation + MLH1 mutation + MSI-H (1)

MSI-H + MSH2 expression + MSH6 expression (1)

TMB-H + MSH6 F1088fs (1)

ER positive + BRCA1 mutation (0)

HRD + BRCA1 mutation (7)

BRCA1 mutation + HR positive (3)

BRCA1 mutation + TMB-H (3)

BRCA1 2080delA + CCNE1 overexpression (2)

BRCA1 mutation + HER-2 negative (2)

HR negative + BRCA1 mutation (2)

HR positive + BRCA1 mutation (2)

BAP1 negative + BRCA1 mutation (1)

BRCA1 hypermethylation (1)

BRCA1 mutation + AKR1C3 overexpression (1)

BRCA1 mutation + BRCA2 mutation + TMB-H (1)

BRCA1 mutation + HER-2 negative + ER positive + PGR positive (1)

BRCA1 mutation + PD-L1 expression (1)

BRCA1 mutation + RAD51B deletion (1)

BRCA1 mutation + RB1 deletion (1)

BRCA1 promoter methylation (1)

EGFR mutation + BRCA1 overexpression (1)

EGFR mutation + BRCA1 underexpression (1)

HR positive + BRCA1 mutation + PALB2 mutation (1)

PTEN deletion + BRCA1 mutation (1)

MSH6 mutation + MLH1 mutation + MSI-H (1)

MSI-H + MSH2 expression + MSH6 expression (1)

TMB-H + MSH6 F1088fs (1)

ER positive + BRCA1 mutation (0)

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MSH2 mutation + MSH6 mutation + BRCA1 mutation

Prostate Cancer

nivolumab + ipilimumab

Sensitive: C4 – Case Studies

nivolumab + ipilimumab

nivolumab + ipilimumab

Sensitive: C4 – Case Studies

nivolumab + ipilimumab