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BIOMARKER:
MSH2 deletion
i
Other names:
MSH2, MutS Homolog 2, HMSH2, MutS (E. Coli) Homolog 2, MutS Homolog 2, Nonpolyposis Type 1, DNA Mismatch Repair Protein Msh2, MutS Protein Homolog 2, HNPCC1, HNPCC, LCFS2, COCA1, FCC1
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Entrez ID:
4436
Related biomarkers:
Expression
Mutation
CNA
Others
‹
MSH2 deletion + MSH6 deletion (3)
MSH2 deletion + MSH6 deletion (0)
MSH2 deletion + MSH6 deletion (3)
MSH2 deletion + MSH6 deletion (0)
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Associations
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VERI cancer hierarchy
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MSH2 deletion
Endometrial Adenocarcinoma
MSH2 deletion
Endometrial Adenocarcinoma
nivolumab
Sensitive: C3 – Early Trials
nivolumab
Sensitive
:
C3
nivolumab
Sensitive: C3 – Early Trials
nivolumab
Sensitive
:
C3
MSH2 deletion
Prostate Cancer
MSH2 deletion
Prostate Cancer
nivolumab
Sensitive: C3 – Early Trials
nivolumab
Sensitive
:
C3
nivolumab
Sensitive: C3 – Early Trials
nivolumab
Sensitive
:
C3
MSH2 deletion
Urothelial Cancer
MSH2 deletion
Urothelial Cancer
durvalumab + MEDI0680
Sensitive: C4 – Case Studies
durvalumab + MEDI0680
Sensitive
:
C4
durvalumab + MEDI0680
Sensitive: C4 – Case Studies
durvalumab + MEDI0680
Sensitive
:
C4
MSH2 deletion
Glioblastoma
MSH2 deletion
Glioblastoma
temozolomide
Resistant: D – Preclinical
temozolomide
Resistant
:
D
temozolomide
Resistant: D – Preclinical
temozolomide
Resistant
:
D
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