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DRUG:

BMS‐986504

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Company:

BMS

Drug class:

PRMT5 inhibitor

Related drugs:

TMB-L + ARID1A deletion + CDKN2A deletion + CDKN2B deletion + MTAP deletion + PIK3R1 N564D + NBN P81fs*23	Gallbladder Cancer	TMB-L + ARID1A deletion + CDKN2A deletion + CDKN2B deletion + MTAP deletion + PIK3R1 N564D + NBN P81fs*23	Gallbladder Cancer	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4
NF1 mutation + CDKN2A deletion + CDKN2B deletion + MTAP deletion	Neurofibrosarcoma	NF1 mutation + CDKN2A deletion + CDKN2B deletion + MTAP deletion	Neurofibrosarcoma	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4
MTAP deletion + CDKN2A deletion + CDKN2B deletion + BAP1 deletion	Malignant Pleural Mesothelioma	MTAP deletion + CDKN2A deletion + CDKN2B deletion + BAP1 deletion	Malignant Pleural Mesothelioma	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4
EGFR mutation + EGFR amplification + MET amplification + MTAP deletion	Non Small Cell Lung Cancer	EGFR mutation + EGFR amplification + MET amplification + MTAP deletion	Non Small Cell Lung Cancer	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4
CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation	Melanoma	CDKN2A deletion + CDKN2B deletion + MTAP deletion + TERT mutation	Melanoma	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4
MTAP deletion + PIK3CA mutation	Malignant Pleural Mesothelioma	MTAP deletion + PIK3CA mutation	Malignant Pleural Mesothelioma	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4	BMS‐986504 Sensitive: C4 – Case Studies BMS‐986504 Sensitive : C4
MTAP deletion	Solid Tumor	MTAP deletion	Solid Tumor	BMS‐986504 Sensitive: D – Preclinical BMS‐986504 Sensitive : D	BMS‐986504 Sensitive: D – Preclinical BMS‐986504 Sensitive : D