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BIOMARKER:
MLH1 deletion+ PMS2 deletion
i
Other names:
MLH1, COCA2, FCC2, HNPCC, HNPCC2, MutL homolog 1, PMS2, PMS1 Homolog 2, Mismatch Repair System Component, PMS1 Homolog 2, Mismatch Repair Protein, Mismatch Repair Endonuclease PMS2, DNA Mismatch Repair Protein PMS2, PMS1 Protein Homolog 2, PMSL2, PMS2 Postmeiotic Segregation Increased 2, Postmeiotic Segregation Increased 2 Nirs Variant 6, PMS2 Postmeiotic Segregation Increased 2, HNPCC4, PMS2CL, MLH4
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Entrez ID:
4292
;
5395
Related biomarkers:
Expression
Mutation
CNA
Others
‹
MSI-H/dMMR + MLH1 deletion + PMS2 deletion (3)
MSI-H/dMMR + MLH1 deletion (2)
ER positive + MLH1 1835del3 + MSI-H/dMMR + TMB-H (1)
MLH1 methylation + MSI-H/dMMR (1)
MLH1 methylation + MSI-H/dMMR + TMB-H (1)
MSH6 mutation + MLH1 mutation + MSI-H (1)
MSI-H/dMMR + MLH1 negative + PMS2 negative (1)
MSI-H/dMMR + PMS2 deletion (1)
MSI-H/dMMR + MLH1 deletion + PMS2 deletion (3)
MSI-H/dMMR + MLH1 deletion (2)
ER positive + MLH1 1835del3 + MSI-H/dMMR + TMB-H (1)
MLH1 methylation + MSI-H/dMMR (1)
MLH1 methylation + MSI-H/dMMR + TMB-H (1)
MSH6 mutation + MLH1 mutation + MSI-H (1)
MSI-H/dMMR + MLH1 negative + PMS2 negative (1)
MSI-H/dMMR + PMS2 deletion (1)
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MLH1 deletion+ PMS2 deletion
Endometrial Cancer
MLH1 deletion+ PMS2 deletion
Endometrial Cancer
dostarlimab-gxly
Sensitive: C3 – Early Trials
dostarlimab-gxly
Sensitive
:
C3
dostarlimab-gxly
Sensitive: C3 – Early Trials
dostarlimab-gxly
Sensitive
:
C3
MLH1 deletion+ PMS2 deletion
Rectal Cancer
MLH1 deletion+ PMS2 deletion
Rectal Cancer
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
nivolumab + ipilimumab
Sensitive
:
C3
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