^
Association details:
| Biomarker: | miR-155 overexpression |
|---|---|
| Cancer: | Diffuse Large B Cell Lymphoma |
| Drug: | cobomarsen (MRG-106) (miR-155 inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Cobomarsen, an oligonucleotide inhibitor of miR-155, slows DLBCL tumor cell growth in vitro and in vivo
Published date:
11/18/2020
Excerpt:
Pre-clinical studies included the delivery of cobomarsen to highly miR-155 expressing ABC-DLBCL cell lines...Cobomarsen decreased cell proliferation, and induced apoptosis in ABC-DLBCL cell lines.
DOI:
10.1158/1078-0432.CCR-20-3139
