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BIOMARKER:

MGMT unmethylation

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Other names: MGMT, Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase
Entrez ID:
Related biomarkers:
MGMT unmethylation
GBM
temozolomide
Sensitive: B - Late Trials
MGMT unmethylation
GBM
nivolumab + ipilimumab
Sensitive: C3 – Early Trials
MGMT unmethylation
GBM
cemiplimab + INO-5401 + INO-9012
Sensitive: C3 – Early Trials
MGMT unmethylation
GBM
VAL-083
Sensitive: C3 – Early Trials
MGMT unmethylation
GBM
pembrolizumab
Resistant: C3 – Early Trials
MGMT unmethylation
GBM
NOX-A12
Sensitive: C3 – Early Trials
MGMT unmethylation
GBM
temozolomide + ABT-888
Sensitive: C3 – Early Trials
MGMT unmethylation
GBM
abemaciclib
Sensitive: C3 – Early Trials