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BIOMARKER:

MGMT promoter methylation

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Other names: MGMT, Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase
Entrez ID:
Related biomarkers:
MGMT promoter methylation
GBM
AV-GBM-1
Sensitive: C3 – Early Trials
SITC 2021 - 3 weeks
MGMT promoter methylation
GBM
temozolomide
Sensitive: A2 - Guideline
MGMT promoter methylation
Anaplastic Astrocytoma
temozolomide
Sensitive: B - Late Trials
MGMT promoter methylation
Ewing Sarcoma
temozolomide + irinotecan
Sensitive: C2 – Inclusion Criteria
MGMT promoter methylation
GBM
cilengitide
Sensitive: C3 – Early Trials
MGMT promoter methylation
Glioma
temozolomide + carmustine
Sensitive: C3 – Early Trials
MGMT promoter methylation
GBM
ruxolitinib
Sensitive: C3 – Early Trials
MGMT promoter methylation
Glioma
ruxolitinib
Sensitive: C3 – Early Trials