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BIOMARKER:

MCL1 overexpression

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Other names: MCL1, MCL1 Apoptosis Regulator BCL2 Family Member, Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1, Myeloid Cell Leukemia Sequence 1 (BCL2-Related), MCL1 BCL2 Family Apoptosis Regulator, Bcl-2-Related Protein EAT/Mcl1, Myeloid Cell Leukemia 1, Bcl-2-Like Protein 3, Bcl2-L-3, Mcl1/EAT, BCL2L3, BCL2 Family Apoptosis Regulator, Myeloid Cell Leukemia ES, MCL1-ES, MCL1L, MCL1S, Mcl-1, EAT, TM
Entrez ID:
Related biomarkers:
MCL1 overexpression
CLL
venetoclax
Resistant: C3 – Early Trials
MCL1 overexpression
Multiple Myeloma
venetoclax
Resistant: D – Preclinical
MCL1 overexpression
Multiple Myeloma
venetoclax
Resistant: D – Preclinical
MCL1 overexpression
AML
venetoclax + ONO-7475
Sensitive: D – Preclinical
MCL1 overexpression
AML
venetoclax + INCB59872
Sensitive: D – Preclinical
MCL1 overexpression
CRC
APG1244 + MCL1 inhibitor
Sensitive: D – Preclinical
MCL1 overexpression
CRC
APG1244
Resistant: D – Preclinical