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BIOMARKER:

LMO7-ALK fusion

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Other names: LMO7, LIM Domain 7, FBX20, F-Box Only Protein 20, KIAA0858, FBXO20, LIM Domain Only Protein 7, LMO-7, LOMP, Zinc-Finger Domain-Containing Protein, LIM Domain Only 7 Protein, F-Box Protein Fbx20, LIM Domain Only 7, LMO7b, NBLST3, CD246, Anaplastic Lymphoma Kinase, Anaplastic Lymphoma Kinase (Ki-1), CD246 Antigen, Mutant Anaplastic Lymphoma Kinase, ALK, ALK Receptor Tyrosine Kinase, Anaplastic Lymphoma Receptor Tyrosine Kinase, ALK Tyrosine Kinase Receptor
Entrez ID:
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Trials
LMO7-ALK fusion
NSCLC
alectinib
Resistant: C3 – Early Trials
J Cell Mol Med - 3 weeks
LMO7-ALK fusion
NSCLC
crizotinib + X-396
Sensitive: C3 – Early Trials
J Cell Mol Med - 3 weeks