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Association details:
Biomarker:
LDH elevation
Cancer:
HER2 Positive Breast Cancer
Drug:
Herceptin (trastuzumab)
(
HER2 inhibitor
)
Direction:
Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Drug Des Devel Ther
Title:
Baseline Lymphopenia: A Predictor Of Poor Outcomes In HER2 positive Metastatic Breast Cancer Treated With Trastuzumab
Published date:
10/29/2019
Excerpt:
...higher LDH was associated with inferior progression-free survival (PFS) (P = 0.045) and OS (P = 0.010).
DOI:
10.2147/DDDT.S212610
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