^
Association details:
Biomarker:LDH elevation + TP53 mutation
Cancer:Diffuse Large B Cell Lymphoma
Regimen:R-CHOP (cyclophosphamide + doxorubicin hydrochloride + prednisone + Rituxan (rituximab) + vincristine)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C4 – Case Studies
Title:

Aggressive Diffuse Intermediate Size B-Cell Lymphoma With P53 Mutation Presented as Primary Bone Marrow Lymphoma

Published date:
12/21/2020
Excerpt:
...PBML case represents a rare intermediate-sized B-cell, not typically recognized as DLBCL, with marked elevated LDH, more than 90% Ki-67 index, with P53 mutation, and showed no response to R-CHOP.
DOI:
10.1177%2F2324709620982765