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Association details:
Biomarker:
KRAS G12D
Cancer:
Pancreatic Cancer
Drug:
BCN057
(
Apoptosis inducer
,
GSK3β inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
AACR 2020
Title:
/ 16 - Preclinical analysis: BCN057 induces apoptosis in Kras mutant tumors
Published date:
06/22/2020
Excerpt:
BCN057 induces apoptosis in Kras mutant pancreatic cancer cells but rescues ISCs of normal epithelial tissue from radiation toxicity which allows intestinal epithelial regeneration…
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