^
Association details:
Biomarker:KRAS G12D
Cancer:Pancreatic Cancer
Drug:BCN057 (Apoptosis inducer, GSK3β inhibitor)
Direction:Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

/ 16 - Preclinical analysis: BCN057 induces apoptosis in Kras mutant tumors

Published date:
06/22/2020
Excerpt:
BCN057 induces apoptosis in Kras mutant pancreatic cancer cells but rescues ISCs of normal epithelial tissue from radiation toxicity which allows intestinal epithelial regeneration…