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Association details:
| Biomarker: | KRAS G12D |
|---|---|
| Cancer: | Pancreatic Adenocarcinoma |
| Drug: | MRTX1133 (KRAS G12D inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
A small molecule with big impact: MRTX1133 targets the KRASG12D mutation in pancreatic cancer
Published date:
10/13/2023
Excerpt:
Here, we provide a summary of the recent advancements related to the use of MRTX1133 for treating KRASG12D-mutant PDAC...MRTX1133 has demonstrated potent in vitro and in vivo antitumor efficacy against KRASG12D-mutant cancer cells...
