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BIOMARKER:

KMT2D mutation + TMB-H

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Other names: KMT2D, Lysine Methyltransferase 2D, Histone-Lysine N-Methyltransferase 2D, Myeloid/Lymphoid Or Mixed-Lineage Leukemia 2, Lysine (K)-Specific Methyltransferase 2D, Trinucleotide Repeat Containing 21, Lysine N-Methyltransferase 2D, ALL1-Related Protein, MLL2, MLL4, ALR, Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein, Histone-Lysine N-Methyltransferase MLL2, Truncated Lysine Methyltransferase 2D, Kabuki Mental Retardation Syndrome, Kabuki Make-Up Syndrome, CAGL114, KABUK1, TNRC21, AAD10, TMB |
Entrez ID:
Related biomarkers:
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Trials
KMT2D mutation + TMB-H
NSCLC
PD-L1 inhibitor
Sensitive: B - Late Trials
KMT2D mutation + TMB-H
NSCLC
PD1 inhibitor + CTLA4 inhibitor
Sensitive: B - Late Trials
KMT2D mutation + TMB-H
CRC
Immunotherapy
Sensitive: C3 – Early Trials