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BIOMARKER:
KMT2C mutation
i
Other names:
MLL3, KMT2C, Lysine Methyltransferase 2C, Histone-Lysine N-Methyltransferase 2C, Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 3, Lysine (K)-Specific Methyltransferase 2C, Histone-Lysine N-Methyltransferase, H3 Lysine-4 Specific, Myeloid/Lymphoid Or Mixed-Lineage Leukemia 3, Histone-Lysine N-Methyltransferase MLL3, Lysine N-Methyltransferase 2C, ALR-Like Protein, KLEFS2
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Entrez ID:
58508
Related biomarkers:
Expression
Mutation
CNA
Others
‹
KMT2C mutation + BCOR mutation + KDM5C mutation (1)
KMT2C mutation + TP53 mutation (1)
KRAS mutation + KMT2C mutation (1)
MLL3 mutation (0)
KMT2C mutation + BCOR mutation + KDM5C mutation (1)
KMT2C mutation + TP53 mutation (1)
KRAS mutation + KMT2C mutation (1)
MLL3 mutation (0)
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Associations
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Trials
VERI cancer hierarchy
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KMT2C mutation
Colorectal Cancer
KMT2C mutation
Colorectal Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
KMT2C mutation
Solid Tumor
KMT2C mutation
Solid Tumor
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
KMT2C mutation
Non Small Cell Lung Cancer
KMT2C mutation
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
KMT2C mutation
Hepatocellular Cancer
KMT2C mutation
Hepatocellular Cancer
PD1 inhibitor + lenvatinib
Sensitive: C3 – Early Trials
PD1 inhibitor + lenvatinib
Sensitive
:
C3
PD1 inhibitor + lenvatinib
Sensitive: C3 – Early Trials
PD1 inhibitor + lenvatinib
Sensitive
:
C3
KMT2C mutation
Renal Cell Carcinoma
KMT2C mutation
Renal Cell Carcinoma
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
KMT2C mutation
Melanoma
KMT2C mutation
Melanoma
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
KMT2C mutation
Bladder Cancer
KMT2C mutation
Bladder Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
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