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Association details:
Biomarker:KLHL6 expression
Cancer:Diffuse Large B Cell Lymphoma
Regimen:R-CHOP
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C4 – Case Studies
Title:

KLHL6 Is Preferentially Expressed in Germinal Center–Derived B-Cell Lymphomas

Published date:
11/11/2017
Excerpt:
Given the impressive prognostic ability of KLHL6 mRNA expression within DLBCL, we investigated whether protein expression by immunohistochemistry in a cohort of 150 R-CHOP–treated DLBCL cases might also predict prognosis. However, in the context of this cohort and using our conditions for immunohistochemistry, no prognostic significance was observed at the protein level.
DOI:
10.1093/ajcp/aqx099