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Association details:
Evidence:
Evidence Level:
Resistant: C4 – Case Studies
New
Title:

Activity of Dasatinib Against L576P KIT Mutant Melanoma: Molecular, Cellular and Clinical Correlates

Excerpt:
Patient A is a 55 year old woman who had resection of a labial mucosal melanoma…Molecular analysis of a lymph node metastasis identified the presence of a L576P KIT mutation. The patient was then treated with adjuvant imatinib 400 mg daily…lymph node representing a recurrence of melanoma while on imatinib.
DOI:
10.1158/1535-7163.MCT-09-0459