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Association details:
Evidence:
Evidence Level:
Resistant: C4 – Case Studies
Title:

Avapritinib in advanced gastrointestinal stromal tumor: case series and review of the literature from a tertiary care center in India

Published date:
01/19/2021
Excerpt:
A 28-year-old male presented with jejunal GIST...Mutation testing was suggestive of exon 17 mutation in the c-KIT domain….After a discussion in the tumor board, the patient was started on avapritinib. He tolerated avapritinib well with greying of hairs and transaminitis (grade 2). A scan was done post 3 months for response evaluation and showed a complete metabolic response and stable disease (Figure 1). The therapy was continued, however, another response assessment was done at 6 months showed PD (Figure 2).
DOI:
10.2144/fsoa-2020-0178