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BIOMARKER:

KIF5B-RET fusion

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Other names: KIF5B, Kinesin Family Member 5B, Conventional Kinesin Heavy Chain, Ubiquitous Kinesin Heavy Chain, Kinesin-1 Heavy Chain, KNS1, UKHC, KNS, Epididymis Secretory Protein Li 61, Kinesin 1 (110-120kD), Kinesin Heavy Chain, HEL-S-61, KINH, RET, Ret Proto-Oncogene, Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret, Cadherin-Related Family Member 16, Rearranged During Transfection, RET Receptor Tyrosine Kinase, Cadherin Family Member 12, Proto-Oncogene C-Ret, CDHF12, CDHR16, PTC, Ret Proto-Oncogene (
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Entrez ID:
KIF5B-RET fusion
Non Small Cell Lung Cancer
RXDX-105
Sensitive
:
C3
KIF5B-RET fusion
Non Small Cell Lung Cancer
lenvatinib
Sensitive
:
C3
KIF5B-RET fusion
Non Small Cell Lung Cancer
sunitinib
Sensitive
:
C3
KIF5B-RET fusion
Non Small Cell Lung Cancer
vandetanib
Sensitive
:
C3
KIF5B-RET fusion
Non Small Cell Lung Cancer
nintedanib
Sensitive
:
C3
KIF5B-RET fusion
Non Small Cell Lung Cancer
cabozantinib capsule
Sensitive
:
C3
KIF5B-RET fusion
Lung Cancer
alectinib
Resistant
:
C3
KIF5B-RET fusion
Lung Adenocarcinoma
nivolumab
Sensitive
:
C4
KIF5B-RET fusion
Non Small Cell Lung Cancer
pembrolizumab
Resistant
:
C4
KIF5B-RET fusion
Non Small Cell Lung Cancer
selpercatinib
Resistant
:
C4
KIF5B-RET fusion
Lung Adenocarcinoma
everolimus + vandetanib
Sensitive
:
C4
KIF5B-RET fusion
Non Small Cell Lung Cancer
cabozantinib tablet
Resistant
:
C4
KIF5B-RET fusion
Lung Adenocarcinoma
cabozantinib tablet
Sensitive
:
D
KIF5B-RET fusion
Lung Adenocarcinoma
vandetanib
Sensitive
:
D
KIF5B-RET fusion
Non Small Cell Lung Cancer
pralsetinib
Sensitive
:
D