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BIOMARKER:

KEAP1 mutation

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Other names: KEAP1, Kelch Like ECH Associated Protein 1, Cytosolic Inhibitor Of Nrf2, Kelch-Like Family Member 19, Kelch-Like Protein 19, KLHL19, INrf2, KEAP1 Delta C, KIAA0132, INRF2
Entrez ID:
Related biomarkers:
KEAP1 mutation
NSCLC
DRP-104
Sensitive: B - Late Trials
KEAP1 mutation
NSCLC
durvalumab
Resistant: B - Late Trials
KEAP1 mutation
Lung Non-Small Cell Squamous Cancer
CB-228
Sensitive: C2 – Inclusion Criteria
KEAP1 mutation
NSCLC
rivoceranib + camrelizumab
Sensitive: C3 – Early Trials
KEAP1 mutation
Lung Non-Squamous Non-Small Cell Cancer
docetaxel
Resistant: C3 – Early Trials
KEAP1 mutation
Lung Non-Squamous Non-Small Cell Cancer
atezolizumab
Resistant: C3 – Early Trials
KEAP1 mutation
Lung Non-Squamous Non-Small Cell Cancer
rivoceranib + camrelizumab
Sensitive: C3 – Early Trials
KEAP1 mutation
NSCLC
atezolizumab
Resistant: C3 – Early Trials
KEAP1 mutation
NSCLC
PD-L1 inhibitor
Sensitive: C3 – Early Trials
KEAP1 mutation
NSCLC
Immunotherapy
Resistant: C3 – Early Trials
KEAP1 mutation
Solid Tumor
IPN60090
Sensitive: C3 – Early Trials
KEAP1 mutation
LUAD
Immunotherapy
Resistant: C3 – Early Trials
KEAP1 mutation
LUAD
DRP-104
Sensitive: D – Preclinical
KEAP1 mutation
Lung Cancer
IPN60090
Sensitive: D – Preclinical