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    Association details:
    Biomarker:JAK2 overexpression
    Cancer:Diffuse Large B Cell Lymphoma
    Drug:EUD-GK-001 (Kinase inhibitor)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    Source:
    AACR-II 2020
    Title:

    Abstract 4206: EUD-GK-001 is a novel kinase inhibitor with in vitro anti-lymphoma activity

    Published date:
    05/15/2020
    Excerpt:
    …three kinases, namely SRC, JAK2 and LCK, were significantly more expressed in EUD-GK-001 GCB-DLBCL sensitive cell lines (DOHH2, FARAGE) than in EUD-GK-001 resistant cells (SU-DHL-8, TOLEDO)…
    DOI:
    10.1158/1538-7445.AM2020-4206