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GENE:

IRF8 (Interferon Regulatory Factor 8)

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FusionPlex™ Pan-Heme panel

FusionPlex™ Pan-Heme panel

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IRF8 overexpression + ER negative	Breast Cancer	IRF8 overexpression + ER negative	Breast Cancer	trastuzumab Sensitive: C3 – Early Trials trastuzumab Sensitive : C3	trastuzumab Sensitive: C3 – Early Trials trastuzumab Sensitive : C3
IRF8 overexpression + ER negative	Breast Cancer	IRF8 overexpression + ER negative	Breast Cancer	FAC Sensitive: C3 – Early Trials FAC Sensitive : C3	FAC Sensitive: C3 – Early Trials FAC Sensitive : C3
IRF8 expression	Prostate Cancer	IRF8 expression	Prostate Cancer	enzalutamide Resistant: C3 – Early Trials enzalutamide Resistant : C3	enzalutamide Resistant: C3 – Early Trials enzalutamide Resistant : C3
IRF8 overexpression + ER negative	Breast Cancer	IRF8 overexpression + ER negative	Breast Cancer	Resistant: C3 – Early Trials Resistant : C3	Resistant: C3 – Early Trials Resistant : C3
IRF8 mutation	Diffuse Large B Cell Lymphoma	IRF8 mutation	Diffuse Large B Cell Lymphoma	axicabtagene ciloleucel Resistant: C3 – Early Trials axicabtagene ciloleucel Resistant : C3	axicabtagene ciloleucel Resistant: C3 – Early Trials axicabtagene ciloleucel Resistant : C3