^
Association details:
| Biomarker: | IRF8 expression |
|---|---|
| Cancer: | Prostate Cancer |
| Drug: | Xtandi (enzalutamide capsule) (Androgen receptor inhibitor) |
| Direction: | Resistant |
Evidence:
Source:
Title:
Loss of a Negative Feedback Loop between IRF8 and AR Promotes Prostate Cancer Growth and Enzalutamide Resistance
Published date:
04/29/2020
Excerpt:
Decreased expression of IRF8 positively associated with CRPC progression and ENZ resistance.
DOI:
10.1158/0008-5472.CAN-19-2549
