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Association details:
Biomarker:
IDH1 mutation
Cancer:
Astrocytoma
Drug:
cisplatin
(
DNA synthesis inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
ADULT GLIOMA: IDH-MUTANT ASTROCYTOMA….Recurrent or Progressive Disease WHO grade 2, KPS ≥60...Useful in Certain Circumstances... If failure or intolerance to the preferred or other recommended regimens…Cisplatin (category 3)
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