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BIOMARKER:
IDH1 mutation + FGFR2 rearrangement
i
Other names:
FGFR2, BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, Fibroblast growth factor receptor 2, HEL-216, HEL-S-26, Epididymis Luminal Protein 216, Isocitrate Dehydrogenase 1 (NADP+), Epididymis Secretory Protein Li 26, IDH1, Isocitrate Dehydrogenase (NADP(+)) 1, Isocitrate Dehydrogenase 1 (NADP+), Soluble
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Entrez ID:
2263
;
3417
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
IDH1 mutation + Chr del(1p) + Chr del(19q) (10)
IDH1 mutation + BRAF V600E (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)
IDH1 mutation + NTRK1 fusion (2)
IDH1 mutation + NTRK2 fusion (2)
IDH1 mutation + NTRK3 fusion (2)
MYC overexpression + IDH1 mutation (2)
BAP1 mutation + FGFR2 fusion (1)
FGFR2 underexpression + FGFR3 mutation (1)
IDH1 mutation + FGFR2 fusion (1)
NOTCH1 positive + FGFR2 mutation (1)
PBRM1 mutation + FGFR2 fusion (1)
TP53 mutation + FGFR2 fusion (1)
IDH wild-type + FGFR3 S249C + TP53 V73fs (1)
IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)
IDH1 mutation + ATRX deletion + TP53 deletion (1)
IDH1 mutation + MGMT promoter methylation (1)
IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)
IDH1 mutation + TMB-L (1)
IDH1 mutation + WT1 overexpression (1)
FGFR2 K660N + TP53 deletion (0)
IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)
IDH1 mutation + Chr del(1p) + Chr del(19q) (10)
IDH1 mutation + BRAF V600E (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)
IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)
IDH1 mutation + NTRK1 fusion (2)
IDH1 mutation + NTRK2 fusion (2)
IDH1 mutation + NTRK3 fusion (2)
MYC overexpression + IDH1 mutation (2)
BAP1 mutation + FGFR2 fusion (1)
FGFR2 underexpression + FGFR3 mutation (1)
IDH1 mutation + FGFR2 fusion (1)
NOTCH1 positive + FGFR2 mutation (1)
PBRM1 mutation + FGFR2 fusion (1)
TP53 mutation + FGFR2 fusion (1)
IDH wild-type + FGFR3 S249C + TP53 V73fs (1)
IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)
IDH1 mutation + ATRX deletion + TP53 deletion (1)
IDH1 mutation + MGMT promoter methylation (1)
IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)
IDH1 mutation + TMB-L (1)
IDH1 mutation + WT1 overexpression (1)
FGFR2 K660N + TP53 deletion (0)
IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)
›
Associations
News
Trials
VERI cancer hierarchy
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IDH1 mutation + FGFR2 rearrangement
Cholangiocarcinoma
IDH1 mutation + FGFR2 rearrangement
Cholangiocarcinoma
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
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