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BIOMARKER:
HR positive + HER-2 underexpression
i
Other names:
PGR, Progesterone receptor, Nuclear receptor subfamily 3 group C member 3, NR3C3, ESR1, Era, ESR, NR3A1, ER, ER beta, ERBB2, CD340, HER-2, HER2, NEU, NGL, V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
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Entrez ID:
2064
;
2099
;
5241
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
ER amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
HER-2 amplification (129)
EGFR amplification + ERBB2 amplification (1)
EGFR exon 19 deletion + HER-2 amplification (1)
HER-2 amplification + MET amplification (1)
HER-2 amplification + PTEN deletion (1)
HER-2 exon 19 deletion (1)
MYC amplification + HER-2 amplification (1)
ER amplification (1)
HER-2 amplification + CDK12 amplification (0)
YES1 amplification + HER-2 amplification (0)
›
Associations
News
Trials
VERI cancer hierarchy
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HR positive + HER-2 underexpression
HER2 Negative Breast Cancer
HR positive + HER-2 underexpression
HER2 Negative Breast Cancer
CDK4 inhibitor + CDK6 inhibitor
Resistant: C3 – Early Trials
CDK4 inhibitor + CDK6 inhibitor
Resistant
:
C3
CDK4 inhibitor + CDK6 inhibitor
Resistant: C3 – Early Trials
CDK4 inhibitor + CDK6 inhibitor
Resistant
:
C3
HR positive + HER-2 underexpression
Breast Cancer
HR positive + HER-2 underexpression
Breast Cancer
U3-1402
Sensitive: C3 – Early Trials
U3-1402
Sensitive
:
C3
U3-1402
Sensitive: C3 – Early Trials
U3-1402
Sensitive
:
C3
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