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DRUG:

Kolupin (tunlametinib)

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Company:

KeChow Pharma

Drug class:

MEK inhibitor

Related drugs:

NRAS mutation	Melanoma	NRAS mutation	Melanoma	tunlametinib Sensitive: C2 – Inclusion Criteria tunlametinib Sensitive : C2	tunlametinib Sensitive: C2 – Inclusion Criteria tunlametinib Sensitive : C2
NRAS Q61	Melanoma	NRAS Q61	Melanoma	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3
NRAS G13R	Melanoma	NRAS G13R	Melanoma	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3
NRAS Q61R	Melanoma	NRAS Q61R	Melanoma	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3
NRAS Q61L	Melanoma	NRAS Q61L	Melanoma	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3
NRAS Q61K	Melanoma	NRAS Q61K	Melanoma	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3
NRAS G12D	Melanoma	NRAS G12D	Melanoma	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3
NRAS G12S	Melanoma	NRAS G12S	Melanoma	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3	tunlametinib Sensitive: C3 – Early Trials tunlametinib Sensitive : C3
BRAF V600	Thyroid Gland Papillary Carcinoma	BRAF V600	Thyroid Gland Papillary Carcinoma	vemurafenib + tunlametinib Sensitive: C3 – Early Trials vemurafenib + tunlametinib Sensitive : C3	vemurafenib + tunlametinib Sensitive: C3 – Early Trials vemurafenib + tunlametinib Sensitive : C3
BRAF V600	Non Small Cell Lung Cancer	BRAF V600	Non Small Cell Lung Cancer	vemurafenib + tunlametinib Sensitive: C3 – Early Trials vemurafenib + tunlametinib Sensitive : C3	vemurafenib + tunlametinib Sensitive: C3 – Early Trials vemurafenib + tunlametinib Sensitive : C3
BRAF V600	Pancreatic Ductal Adenocarcinoma	BRAF V600	Pancreatic Ductal Adenocarcinoma	vemurafenib + tunlametinib Sensitive: C3 – Early Trials vemurafenib + tunlametinib Sensitive : C3	vemurafenib + tunlametinib Sensitive: C3 – Early Trials vemurafenib + tunlametinib Sensitive : C3
BRAF V600	Colorectal Cancer	BRAF V600	Colorectal Cancer	vemurafenib + tunlametinib Sensitive: C3 – Early Trials vemurafenib + tunlametinib Sensitive : C3	vemurafenib + tunlametinib Sensitive: C3 – Early Trials vemurafenib + tunlametinib Sensitive : C3