^
Association details:
| Biomarker: | GATA6 underexpression |
|---|---|
| Cancer: | Pancreatic Ductal Adenocarcinoma |
| Drug: | leucovorin calcium (Folate analog) |
| Direction: | Resistant |
Evidence:
Source:
Title:
GATA6 regulates EMT and tumour dissemination, and is a marker of response to adjuvant chemotherapy in pancreatic cancer
Excerpt:
Patients with basal-like GATA6low tumours have a shorter survival and have a distinctly poor response to adjuvant 5-fluorouracil (5-FU)/leucovorin.
DOI:
10.1136/gutjnl-2015-311256
