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DRUG CLASS:

GAS6 inhibitor

DRUG CLASS:

GAS6 inhibitor

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No biomarker	Clear Cell Renal Cell Carcinoma	No biomarker	Clear Cell Renal Cell Carcinoma	AVB-500 Sensitive: B - Late Trials AVB-500 Sensitive : B	AVB-500 Sensitive: B - Late Trials AVB-500 Sensitive : B
GAS6 elevation	Ovarian Cancer	GAS6 elevation	Ovarian Cancer	olaparib + AVB-500 Resistant: C3 – Early Trials olaparib + AVB-500 Resistant : C3	olaparib + AVB-500 Resistant: C3 – Early Trials olaparib + AVB-500 Resistant : C3
GAS6 overexpression	Ovarian Cancer	GAS6 overexpression	Ovarian Cancer	olaparib + AVB-500 Resistant: C3 – Early Trials olaparib + AVB-500 Resistant : C3	olaparib + AVB-500 Resistant: C3 – Early Trials olaparib + AVB-500 Resistant : C3
AXL elevation + GAS6 elevation	Clear Cell Renal Cell Carcinoma	AXL elevation + GAS6 elevation	Clear Cell Renal Cell Carcinoma	cabozantinib tablet + AVB-500 Sensitive: C3 – Early Trials cabozantinib tablet + AVB-500 Sensitive : C3	cabozantinib tablet + AVB-500 Sensitive: C3 – Early Trials cabozantinib tablet + AVB-500 Sensitive : C3