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GENE:

FOXA1 (Forkhead Box A1)

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FOXA1 overexpression	Triple Negative Breast Cancer	FOXA1 overexpression	Triple Negative Breast Cancer	carboplatin + docetaxel Resistant: C3 – Early Trials carboplatin + docetaxel Resistant : C3	carboplatin + docetaxel Resistant: C3 – Early Trials carboplatin + docetaxel Resistant : C3
FOXA mutation	Prostate Cancer	FOXA mutation	Prostate Cancer	abiraterone acetate + RG7440 Resistant: C3 – Early Trials abiraterone acetate + RG7440 Resistant : C3	abiraterone acetate + RG7440 Resistant: C3 – Early Trials abiraterone acetate + RG7440 Resistant : C3
FOXA1 expression + ER positive	HER2 Negative Breast Cancer	FOXA1 expression + ER positive	HER2 Negative Breast Cancer	tamoxifen Sensitive: C3 – Early Trials tamoxifen Sensitive : C3	tamoxifen Sensitive: C3 – Early Trials tamoxifen Sensitive : C3
FOXA1 mutation	Estrogen Receptor Positive Breast Cancer	FOXA1 mutation	Estrogen Receptor Positive Breast Cancer	Aromatase inhibitor Resistant: D – Preclinical Aromatase inhibitor Resistant : D	Aromatase inhibitor Resistant: D – Preclinical Aromatase inhibitor Resistant : D
FOXA1 overexpression	Breast Cancer	FOXA1 overexpression	Breast Cancer	ribociclib Sensitive: D – Preclinical ribociclib Sensitive : D	ribociclib Sensitive: D – Preclinical ribociclib Sensitive : D