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Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Source:
Title:

A Novel Combination Regimen of BET and FLT3 Inhibition for FLT3-ITD Acute Myeloid Leukemia

Published date:
11/06/2019
Excerpt:
...taking 120 mg daily of PLX51107 and 60 mg daily of quizartinib), the combination induced synergistic cytotoxicity in a series of 10 different FLT3-ITD AML patient blast samples co-cultured with bone marrow stroma (Figure 3).
DOI:
10.1182/blood-2019-124030