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Association details:
Evidence:
Evidence Level:
Sensitive: D – Preclinical
Title:

The Multi-Kinase Inhibitor EC-70124 Is a Promising Candidate for the Treatment of FLT3-ITD-Positive Acute Myeloid Leukemia

Published date:
03/21/2022
Excerpt:
Orally disposable EC-70124 exerted a potent inhibitory effect on the growth of FLT3-ITD MUT AML cells, delaying disease progression and debulking the leukemia. Collectively, our findings show that EC-70124 is a promising and safe agent for the treatment of AML with FLT3-ITD mutation.
DOI:
10.3390/cancers14061593