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BIOMARKER:

FLT3-ITD mutation + IDH1 mutation

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Entrez ID:

Related biomarkers:

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IDH1 mutation + Chr del(1p) + Chr del(19q) (10)

NUP98-NSD1 fusion + FLT3-ITD mutation (3)

IDH1 mutation + BRAF V600E (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)

IDH1 mutation + NTRK1 fusion (2)

IDH1 mutation + NTRK2 fusion (2)

IDH1 mutation + NTRK3 fusion (2)

MYC overexpression + IDH1 mutation (2)

CD123 positive + FLT3-ITD mutation (1)

CSK overexpression + FLT3-ITD mutation (1)

EPHB2 overexpression + FLT3-ITD mutation (1)

FLT3 A848P + MLL-MLLT3 fusion (1)

FLT3 wild-type + TP53 mutation (1)

FLT3-ITD mutation + MLL fusion + TP53 mutation (1)

FLT3-ITD mutation + PML-RARA fusion + WT1 overexpression (1)

FLT3-ITD mutation + RIPK1 expression (1)

FLT3-ITD mutation + SKI overexpression (1)

HCK overexpression + FLT3-ITD mutation (1)

HLF overexpression + FLT3-ITD mutation (1)

KAT6A-CREBBP fusion + FLT3-TKD mutation (1)

LYN overexpression + FLT3-ITD mutation (1)

miR-155 deletion + FLT3-ITD mutation (1)

IDH wild-type + FGFR3 S249C + TP53 V73fs (1)

IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)

IDH1 mutation + ATRX deletion + TP53 deletion (1)

IDH1 mutation + FGFR2 fusion (1)

IDH1 mutation + FGFR2 rearrangement (1)

IDH1 mutation + MGMT promoter methylation (1)

IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)

IDH1 mutation + TMB-L (1)

IDH1 mutation + WT1 overexpression (1)

IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)

IDH1 mutation + Chr del(1p) + Chr del(19q) (10)

NUP98-NSD1 fusion + FLT3-ITD mutation (3)

IDH1 mutation + BRAF V600E (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK1 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK2 fusion (2)

IDH1 mutation + Chr del(1p) + Chr del(19q) + NTRK3 fusion (2)

IDH1 mutation + NTRK1 fusion (2)

IDH1 mutation + NTRK2 fusion (2)

IDH1 mutation + NTRK3 fusion (2)

MYC overexpression + IDH1 mutation (2)

CD123 positive + FLT3-ITD mutation (1)

CSK overexpression + FLT3-ITD mutation (1)

EPHB2 overexpression + FLT3-ITD mutation (1)

FLT3 A848P + MLL-MLLT3 fusion (1)

FLT3 wild-type + TP53 mutation (1)

FLT3-ITD mutation + MLL fusion + TP53 mutation (1)

FLT3-ITD mutation + PML-RARA fusion + WT1 overexpression (1)

FLT3-ITD mutation + RIPK1 expression (1)

FLT3-ITD mutation + SKI overexpression (1)

HCK overexpression + FLT3-ITD mutation (1)

HLF overexpression + FLT3-ITD mutation (1)

KAT6A-CREBBP fusion + FLT3-TKD mutation (1)

LYN overexpression + FLT3-ITD mutation (1)

miR-155 deletion + FLT3-ITD mutation (1)

IDH wild-type + FGFR3 S249C + TP53 V73fs (1)

IDH1 R132S + H3K27me3 loss + MET exon 14 skipping mutation (1)

IDH1 mutation + ATRX deletion + TP53 deletion (1)

IDH1 mutation + FGFR2 fusion (1)

IDH1 mutation + FGFR2 rearrangement (1)

IDH1 mutation + MGMT promoter methylation (1)

IDH1 mutation + MYC amplification + MAPRE1 overexpression (1)

IDH1 mutation + TMB-L (1)

IDH1 mutation + WT1 overexpression (1)

IDH1 mutation + Chr del(1p) + Chr del(19q) + MGMT promoter methylation (0)

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FLT3-ITD mutation + IDH1 mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation + IDH1 mutation	Acute Myelogenous Leukemia	FLT3 inhibitor Sensitive: C3 – Early Trials FLT3 inhibitor Sensitive : C3	FLT3 inhibitor Sensitive: C3 – Early Trials FLT3 inhibitor Sensitive : C3
FLT3-ITD mutation + IDH1 mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation + IDH1 mutation	Acute Myelogenous Leukemia	IDH1 inhibitor Sensitive: C3 – Early Trials IDH1 inhibitor Sensitive : C3	IDH1 inhibitor Sensitive: C3 – Early Trials IDH1 inhibitor Sensitive : C3