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BIOMARKER:

FGFR2-AFF4 fusion

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Other names: FGFR2, BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25, Fibroblast growth factor receptor 2, AFF4, AF4/FMR2 Family Member 4, Major CDK9 Elongation Factor-Associated Protein, ALL1-Fused Gene From Chromosome 5q31 Protein, AF5Q31, MCEF, ALL1 Fused Gene From 5q31, AF4/FMR2 Family, Member 4, Protein AF-5q31
Entrez ID:
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Trials
FGFR2-AFF4 fusion
Cholangiocarcinoma
pemigatinib + TP-0903
Sensitive: D – Preclinical
FGFR2-AFF4 fusion
Cholangiocarcinoma
pemigatinib + BGB324
Sensitive: D – Preclinical
FGFR2-AFF4 fusion
Cholangiocarcinoma
TP-0903
Sensitive: D – Preclinical
FGFR2-AFF4 fusion
Cholangiocarcinoma
BGB324
Sensitive: D – Preclinical
FGFR2-AFF4 fusion
Cholangiocarcinoma
pemigatinib
Resistant: D – Preclinical