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BIOMARKER:
FGFR1 mutation
i
Other names:
FGFR1, BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM, Fibroblast growth factor receptor 1
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Entrez ID:
2260
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
FGFR1 rearrangement (3)
FGFR1 T141R (2)
FGFR1 A354V (1)
FGFR1 V561M (1)
FGFR1 rearrangement (3)
FGFR1 T141R (2)
FGFR1 A354V (1)
FGFR1 V561M (1)
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Trials
VERI cancer hierarchy
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FGFR1 mutation
Breast Cancer
FGFR1 mutation
Breast Cancer
GDC-0032
Resistant: B - Late Trials
GDC-0032
Resistant
:
B
GDC-0032
Resistant: B - Late Trials
GDC-0032
Resistant
:
B
FGFR1 mutation
Non Small Cell Lung Cancer
FGFR1 mutation
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
FGFR1 mutation
Non Small Cell Lung Cancer
FGFR1 mutation
Non Small Cell Lung Cancer
nintedanib
Sensitive: C3 – Early Trials
nintedanib
Sensitive
:
C3
nintedanib
Sensitive: C3 – Early Trials
nintedanib
Sensitive
:
C3
FGFR1 mutation
Urothelial Cancer
FGFR1 mutation
Urothelial Cancer
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
FGFR1 mutation
Melanoma
FGFR1 mutation
Melanoma
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
PD1 inhibitor
Sensitive: C3 – Early Trials
PD1 inhibitor
Sensitive
:
C3
FGFR1 mutation
Melanoma
FGFR1 mutation
Melanoma
CTLA4 inhibitor
Sensitive: C3 – Early Trials
CTLA4 inhibitor
Sensitive
:
C3
CTLA4 inhibitor
Sensitive: C3 – Early Trials
CTLA4 inhibitor
Sensitive
:
C3
FGFR1 mutation
Melanoma
FGFR1 mutation
Melanoma
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
PD-L1 inhibitor
Sensitive: C3 – Early Trials
PD-L1 inhibitor
Sensitive
:
C3
FGFR1 mutation
Urothelial Cancer
FGFR1 mutation
Urothelial Cancer
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
FGFR1 mutation
Solid Tumor
FGFR1 mutation
Solid Tumor
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
FGFR1 mutation
Glioma
FGFR1 mutation
Glioma
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
erdafitinib
Sensitive: C3 – Early Trials
erdafitinib
Sensitive
:
C3
FGFR1 mutation
Solid Tumor
FGFR1 mutation
Solid Tumor
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
futibatinib
Sensitive: C3 – Early Trials
futibatinib
Sensitive
:
C3
FGFR1 mutation
Esophageal Cancer
FGFR1 mutation
Esophageal Cancer
pemigatinib
Sensitive: C3 – Early Trials
pemigatinib
Sensitive
:
C3
pemigatinib
Sensitive: C3 – Early Trials
pemigatinib
Sensitive
:
C3
FGFR1 mutation
Solid Tumor
FGFR1 mutation
Solid Tumor
CPL304110
Sensitive: D – Preclinical
CPL304110
Sensitive
:
D
CPL304110
Sensitive: D – Preclinical
CPL304110
Sensitive
:
D
FGFR1 mutation
Estrogen Receptor Positive Breast Cancer
FGFR1 mutation
Estrogen Receptor Positive Breast Cancer
fulvestrant
Resistant: D – Preclinical
fulvestrant
Resistant
:
D
fulvestrant
Resistant: D – Preclinical
fulvestrant
Resistant
:
D
FGFR1 mutation
Estrogen Receptor Positive Breast Cancer
FGFR1 mutation
Estrogen Receptor Positive Breast Cancer
palbociclib
Resistant: D – Preclinical
palbociclib
Resistant
:
D
palbociclib
Resistant: D – Preclinical
palbociclib
Resistant
:
D
FGFR1 mutation
Gastric Cancer
FGFR1 mutation
Gastric Cancer
erdafitinib
Sensitive: D – Preclinical
erdafitinib
Sensitive
:
D
erdafitinib
Sensitive: D – Preclinical
erdafitinib
Sensitive
:
D
FGFR1 mutation
Squamous Cell Carcinoma of Head and Neck
FGFR1 mutation
Squamous Cell Carcinoma of Head and Neck
ABSK091 + AZD2014
Sensitive: D – Preclinical
ABSK091 + AZD2014
Sensitive
:
D
ABSK091 + AZD2014
Sensitive: D – Preclinical
ABSK091 + AZD2014
Sensitive
:
D
FGFR1 mutation
Solid Tumor
FGFR1 mutation
Solid Tumor
eFT226
Sensitive: D – Preclinical
eFT226
Sensitive
:
D
eFT226
Sensitive: D – Preclinical
eFT226
Sensitive
:
D
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