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Association details:
Biomarker:
FGFR1 expression
Cancer:
Squamous Cell Carcinoma of Head and Neck
Drug:
Truseltiq (infigratinib)
(
FGFR inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Source:
Clin Cancer Res
Title:
FGFR1 expression levels predict BGJ398-sensitivity of FGFR1-dependent head and neck squamous cell cancers
Excerpt:
FGFR1 expression associates with BGJ398 sensitivity in HNSCC cell lines and predicts tyrosine kinase inhibitor sensitivity in PDXs.
DOI:
10.1158/1078-0432.CCR-14-3357
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