^
    Back
    Association details:
    Biomarker:FGFR1 amplification
    Cancer:Lung Non-Small Cell Squamous Cancer
    Drug:fexagratinib (ABSK091) (pan-FGFR inhib)
    Direction:Sensitive
    Evidence:
    Evidence Level:
    Sensitive: D – Preclinical
    New
    Source:
    Clin Cancer Res
    Title:

    Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models

    Excerpt:
    AZD4547 induced potent tumor stasis or regressive effects in four of five FGFR1-amplified squamous NSCLC PDTX models.
    DOI:
    10.1158/1078-0432.CCR-12-2694