^
Association details:
| Biomarker: | FGFR1 amplification |
|---|---|
| Cancer: | Lung Non-Small Cell Squamous Cancer |
| Drug: | fexagratinib (ABSK091) (FGFR inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Translating the therapeutic potential of AZD4547 in FGFR1-amplified non-small cell lung cancer through the use of patient-derived tumor xenograft models
Excerpt:
AZD4547 induced potent tumor stasis or regressive effects in four of five FGFR1-amplified squamous NSCLC PDTX models.
DOI:
10.1158/1078-0432.CCR-12-2694
