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BIOMARKER:

FGFR1 amplification + RAF1 amplification + CDK6 amplification

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Other names: FGFR1, BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM, Fibroblast growth factor receptor 1, RAF1, Raf-1 Proto-Oncogene Serine/Threonine Kinase, RAF Proto-Oncogene Serine/Threonine-Protein Kinase, V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1, C-Raf Proto-Oncogene Serine/Threonine Kinase, Proto-Oncogene C-RAF, Raf-1, V-Raf-1 Murine Leukemia Viral Oncogene-Like Protein 1, Raf Proto-Oncogene Serine/Threonine Protein Kinase, Oncogene RAF1, CMD1NN, C-Raf, CRAF, CRaf, NS5, RAF, CDK6, PLSTIRE, Cyclin-dependent kinase 6
Entrez ID:
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Trials
FGFR1 amplification + RAF1 amplification + CDK6 amplification
Small Cell Lung Cancer
nivolumab
Resistant: C4 – Case Studies
FGFR1 amplification + RAF1 amplification + CDK6 amplification
Small Cell Lung Cancer
ponatinib
Resistant: C4 – Case Studies