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Association details:
| Biomarker: | ER positive |
|---|---|
| Cancer: | Estrogen Receptor Positive Breast Cancer |
| Drug: | Erleada (apalutamide) (Androgen receptor antagonist) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Hormone receptor inhibition as a strategy for radiosensitization of breast cancer
Published date:
05/15/2020
Excerpt:
AR inhibition with enzalutamide, apalutamide, and darolutamide showed limited single agent growth inhibition efficacy in AR+ TNBC and AR+, ER+ breast cancer cell lines (IC50 > 10 μM).
