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Association details:
Biomarker:EML4-ALK fusion
Cancer:Lung Adenocarcinoma
Regimen:GC (cisplatin + gemcitabine)
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C4 – Case Studies
Title:

Case Report: Neoadjuvant and Adjuvant Crizotinib Targeted Therapy in Stage IIIA-N2 ALK-Positive Non-Small-Cell Lung Cancer

Published date:
03/17/2021
Excerpt:
A 27-year-old man was diagnosed with a stage IIIAcT3N2M0 (7thUICC/AJCC) upper left lung adenocarcinoma harboring EML4-ALK fusion...Poor tumor response was observed after 3 cycles of chemotherapy (gemcitabine plus cisplatin)...
DOI:
https://doi.org/10.3389/fonc.2021.655856