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DRUG:

Orserdu (elacestrant)

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Company:

DRI Healthcare, Menarini, Radius, SciClone

Drug class:

Selective estrogen receptor degrader

Related drugs:

ER positive + ESR1 mutation	HER2 Negative Breast Cancer	ER positive + ESR1 mutation	HER2 Negative Breast Cancer	elacestrant Sensitive: A1 - Approval elacestrant Sensitive : A1	elacestrant Sensitive: A1 - Approval elacestrant Sensitive : A1
ESR1 mutation + HR positive	HER2 Negative Breast Cancer	ESR1 mutation + HR positive	HER2 Negative Breast Cancer	elacestrant Sensitive: A2 - Guideline elacestrant Sensitive : A2	elacestrant Sensitive: A2 - Guideline elacestrant Sensitive : A2
ER positive	HER2 Negative Breast Cancer	ER positive	HER2 Negative Breast Cancer	elacestrant Sensitive: B - Late Trials elacestrant Sensitive : B	elacestrant Sensitive: B - Late Trials elacestrant Sensitive : B
ER positive	Estrogen Receptor Positive Breast Cancer	ER positive	Estrogen Receptor Positive Breast Cancer	elacestrant Sensitive: B - Late Trials elacestrant Sensitive : B	elacestrant Sensitive: B - Late Trials elacestrant Sensitive : B
ER mutation	Estrogen Receptor Positive Breast Cancer	ER mutation	Estrogen Receptor Positive Breast Cancer	elacestrant Sensitive: C2 – Inclusion Criteria elacestrant Sensitive : C2	elacestrant Sensitive: C2 – Inclusion Criteria elacestrant Sensitive : C2
PIK3CA wild-type+ ESR1 wild-type	Breast Cancer	PIK3CA wild-type+ ESR1 wild-type	Breast Cancer	MEN1611 + elacestrant Sensitive: D – Preclinical MEN1611 + elacestrant Sensitive : D	MEN1611 + elacestrant Sensitive: D – Preclinical MEN1611 + elacestrant Sensitive : D
PIK3CA mutation + ESR1 wild-type	Breast Cancer	PIK3CA mutation + ESR1 wild-type	Breast Cancer	MEN1611 + elacestrant Sensitive: D – Preclinical MEN1611 + elacestrant Sensitive : D	MEN1611 + elacestrant Sensitive: D – Preclinical MEN1611 + elacestrant Sensitive : D
PIK3CA mutation + ESR1 mutation	Breast Cancer	PIK3CA mutation + ESR1 mutation	Breast Cancer	MEN1611 + elacestrant Sensitive: D – Preclinical MEN1611 + elacestrant Sensitive : D	MEN1611 + elacestrant Sensitive: D – Preclinical MEN1611 + elacestrant Sensitive : D
ER positive + PIK3CA H1047R	Breast Cancer	ER positive + PIK3CA H1047R	Breast Cancer	elacestrant + OKI-219 Sensitive: D – Preclinical elacestrant + OKI-219 Sensitive : D	elacestrant + OKI-219 Sensitive: D – Preclinical elacestrant + OKI-219 Sensitive : D