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Association details:
Biomarker:EGFR overexpression
Cancer:Colorectal Cancer
Drug Class:EGFR inhibitor
Direction:Resistant
Evidence:
Evidence Level:
Resistant: C3 – Early Trials
Source:
Title:

Expression of podocalyxin-like protein and epidermal growth factor receptor in metastatic colorectal cancer: Prognostic impact and relationship with response to cetuximab.

Published date:
05/16/2018
Excerpt:
...454 mCRC patients from three Scandinavian countries...Both high expression of PODXL and EGFR was significantly associated with a reduced OS (HR = 1.86; 95% CI 1.29-2.69, and HR = 1.39; 95% CI 1.06-1.84, respectively)….
DOI:
10.1200/JCO.2018.36.15_suppl.e15587