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Association details:
Biomarker:
EGFR overexpression
Cancer:
Breast Cancer
Drug:
Caprelsa (vandetanib)
(
Multi-tyrosine kinase inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: D – Preclinical
New
Source:
Int J Cancer
Title:
Vandetanib as a potential new treatment for estrogen receptor-negative breast cancers
Excerpt:
Vandetanib induced tumor regression in PDX models with high expression of RET or EGFR.
DOI:
10.1002/ijc.29974
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