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Association details:
| Biomarker: | EGFR L747S |
|---|---|
| Cancer: | Non Small Cell Lung Cancer |
| Drug: | Gilotrif (afatinib) (EGFR inhibitor, HER2 inhibitor, HER4 inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Molecular Characteristics and Response to EGFR TKIs of EGFR L747 Position Mutation in Lung Cancer Patients.
Published date:
01/12/2021
Excerpt:
...patients treated with EGFR TKIs...and two EGFR L747S patient achieved progressive disease to icotinib treatment....EGFR L747 mutations account for 0.4% in EGFR mutated NSCLC patients and EGFR L747P/S/V were common mutations identified.
