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Association details:
| Biomarker: | EGFR G719C + EGFR E709V |
|---|---|
| Cancer: | Small Cell Lung Cancer |
| Drug: | Gilotrif (afatinib) (EGFR inhibitor, HER2 inhibitor, HER4 inhibitor) |
| Direction: | Sensitive |
Evidence:
Source:
Title:
Complete Remission to Afatinib in a Patient Harboring a Novel Epidermal Growth Factor Mutation in De Novo Small-Cell Lung Cancer: A Case Report
Published date:
11/10/2021
Excerpt:
We report on a case of EGFR-mutated de novo SCLC with 2 activating EGFR mutations in exon 18 (G719C, E709V) in a 56-year-old woman who responded to afatinib with good tolerability.
DOI:
https://doi.org/10.1016/j.cllc.2021.11.002
