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Association details:
Evidence:
Evidence Level:
Sensitive: B - Late Trials
Source:
Title:

LBA50 - ACTIVE: Apatinib plus gefitinib versus placebo plus gefitinib as first-line treatment for advanced epidermal growth factor receptor-mutant (EGFRm) non-small-cell lung cancer (NSCLC): A multicentered, randomized, double-blind, placebo-controlled phase III trial (CTONG1706)

Published date:
09/19/2020
Excerpt:
...Pts with ex19del had better HR than L858R (HR = 0.67, 0.45-0.99; 0.72, 0.48-1.09)...Prolonged PFS by INV (HR = 0.71, 95% CI 0.53-0.95) was observed...ORR was 77.1% and 73.7% in AG and G arms (p = 0.5572)…
Trial ID:
Evidence Level:
Sensitive: C2 – Inclusion Criteria
New
Go to data
Title:

A Study of Gefitinib With or Without Apatinib in Patients With Advanced Non-squamous Non-Small-Cell Lung Cancer Harboring EGFR Mutations

Excerpt:
...Documented evidence of tumor harboring an activating EGFR mutation (Example 19 del and L858R)...
Trial ID: