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BIOMARKER:
EGFR exon 19 deletion + BRAF V600E
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor, BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threonine-protein kinase, Murine sarcoma viral (V-Raf) oncogene homolog B1, B-raf serine/threonine-protein, 94 KDa B-raf protein, B-RAF1
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Entrez ID:
1956
;
673
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
KIAA1549-BRAF fusion (10)
BRAF fusion (9)
EGFR-RAD51 fusion (5)
AGK-BRAF fusion (5)
SKAP2-BRAF fusion (4)
TARDBP-BRAF fusion (4)
FKBP15-BRAF fusion (3)
PPFIBP2-BRAF fusion (3)
EGFR-SEPTIN14 fusion (2)
CUL1-BRAF fusion (2)
SLC45A3-BRAF fusion (2)
SND1-BRAF fusion (2)
EGFR fusion (1)
EGFR-GRB2 fusion (1)
KIF5B-EGFR fusion (1)
BRAF-MAD1L1 fusion (1)
BRAF-ZC3H7A fusion (1)
CUX1-BRAF fusion (1)
EXOC4-BRAF fusion (1)
NRF1-BRAF fusion (1)
TRIM33-BRAF fusion (1)
ZKSCAN1-BRAF fusion (1)
EGFR fusion + RAD51 fusion (0)
KIAA1549-BRAF fusion (10)
BRAF fusion (9)
EGFR-RAD51 fusion (5)
AGK-BRAF fusion (5)
SKAP2-BRAF fusion (4)
TARDBP-BRAF fusion (4)
FKBP15-BRAF fusion (3)
PPFIBP2-BRAF fusion (3)
EGFR-SEPTIN14 fusion (2)
CUL1-BRAF fusion (2)
SLC45A3-BRAF fusion (2)
SND1-BRAF fusion (2)
EGFR fusion (1)
EGFR-GRB2 fusion (1)
KIF5B-EGFR fusion (1)
BRAF-MAD1L1 fusion (1)
BRAF-ZC3H7A fusion (1)
CUX1-BRAF fusion (1)
EXOC4-BRAF fusion (1)
NRF1-BRAF fusion (1)
TRIM33-BRAF fusion (1)
ZKSCAN1-BRAF fusion (1)
EGFR fusion + RAD51 fusion (0)
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Trials
VERI cancer hierarchy
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EGFR exon 19 deletion + BRAF V600E
Lung Adenocarcinoma
EGFR exon 19 deletion + BRAF V600E
Lung Adenocarcinoma
trametinib + osimertinib + dabrafenib
Sensitive: C4 – Case Studies
trametinib + osimertinib + dabrafenib
Sensitive
:
C4
trametinib + osimertinib + dabrafenib
Sensitive: C4 – Case Studies
trametinib + osimertinib + dabrafenib
Sensitive
:
C4
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